磺胺硝苯

Sulfanitran chemical formula C14H13N3O5S , CAS No. 122-16-7, other names: 4´-[(p-nitrophenyl)sulfamoyl]acetylanilide; N4-acetyl-N1-(p-nitrophenyl) phenyl)sulfonamide; 4-acetylaminobenzenesulfon-4III-nitroaniline; N-(acetylaminobenzenesulfonyl)-p-nitroaniline, APNPS.

Sulfonamide is a sulfonamide antibiotic used in the poultry industry as an antibacterial and anticoccidial agent used in poultry feed. Sulfanitran is also a multidrug resistance protein 2 (MRP2) stimulator, increasing the affinity of MRP2 for estradiol-17-β-D-glucuronide (E217βG).

It is a component of Novastat, Polystat and Unistat, brands of feed additives used to control Coccidioides in chickens

drug interactions

  • The combined use of acarbose and sulfonate can improve the therapeutic effect.
  • The combined use of acetamide and sulfonate can improve the therapeutic effect.
  • The combined use of albiglutide and sulfonate can improve the therapeutic effect.
  • The combined use of alogliptin and sulfonate may increase the therapeutic effect.
  • Benzylpenicillin Sulfonatebenzene may decrease the excretion rate of Benzylpenicillin which could result in a higher serum level.

Review

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