synonyms
- N-Acetyl-L-methionine
- 65-82-7
- N-Acetylmethionine
- Acetyl-L-methionine
- Methionamine
- N-acetyl-L-methionine
- 65-82-7
- N-acetylmethionine
- Acetyl-L-Methionine
- Methylthiamine
Molecular formula
C7H13NO3S
melting point
105.5℃
storage
powder
-20°C 3 years
4°C 2 years
in solvent
-80°C 2 years
-20°C 1 year
code
- DSSTox substance ID DTXSID00883214
- DSSTOX compound identifier DTXCID701022763
- NSC number 118514
- EC number 200-617-7
- ECHA Substance Infocard ID 100.000.561
- RxNorm ID 1426463
- DrugBank ID 01646
- Human Metabolome Database ID HMDB0011745
- UNII 9J12WX5B6A
- Probes And Drugs ID PD008892
- KEGG ID C02712
- PDB ligand ID AME
- CAB ID 4494
describe
N-Acetyl-L-methionine is a derivative of L-methionine, which is L-methionine in which one of the amine hydrogens is replaced by an acetyl group. It has the function of nutritional supplement. It is N-acetyl-L-amino acid, L-methionine derivative and N-acetylmethionine. It is the conjugate acid of N-acetyl-L-methionine (1-). It is the enantiomer of N-acetyl-D-methionine.
N-acetyl-L-methionine is a metabolite found or produced in Escherichia coli (strain K12, MG1655).
N-acetyl-L-methionine is a natural product found in Arabidopsis thaliana, ginseng, and other organisms for which data are available.
N-acetyl-L-methionine is a human metabolite that is nutritionally and metabolically equivalent to L-methionine. L-methionine is an indispensable amino acid required for normal growth and development.
N-acetylmethionine is an amino acid used in the peritoneal dialysis treatment of patients with renal failure and in the nutritional therapy of patients with nutritional deficiencies or debility following infection.
N-acetyl-L-methionine is an excellent protector of human serum albumin against post-translational oxidation
Research shows that N- AcMet , N-acetyl-L-methionine is excellent at scavenging reactive oxygen species and protecting proteins from oxidation. N-AcMet has a good stabilizing effect on protein structure and its antioxidant properties. The reduction in oxidized recombinant human serum albumin (rHSA, Recombinant human serum albumin) burden helps maintain normal pharmacokinetics. Therefore, N-AcMet should be useful as a novel stabilizer and antioxidant for albumin and other solubilized protein preparations. It is expected that N-AcMet will be approved as a new stabilizer in the near future.
