Pyrroloquinoline quinone ( PQQ; Pyrroloquinoline quinone), also known as methoxybutane, is a compound that acts as a cofactor for certain enzymes involved in cell function. PQQ supports proper mitochondrial function and cellular development of new mitochondria, but its exact mechanism remains unclear .
It has gained attention for its potential health benefits. PQQ is often called the longevity vitamin.
PQQ is a vitamin-like compound found in kiwi fruit, spinach, soybeans, breast milk and soil. It is actually produced by bacteria. In fact, within bacteria, PQQ helps break down alcohol and sugar and convert them into energy. Many plants eventually absorb PQQ through the soil.
PQQ plays a vital role as a cofactor for enzymes involved in cellular energy production, particularly in the mitochondria. Mitochondria are energy-producing organelles within cells.
How does PQQ work?
Antioxidant properties
PQQ has antioxidant properties, which means it can help neutralize free radicals in the body. Free radicals are reactive molecules that cause oxidative stress and damage cells.
anti-inflammatory properties
PQQ has been studied for its anti-inflammatory effects. Inflammation is the body's natural response to injury or infection, but chronic inflammation can lead to a variety of health problems.
cellular energy production
PQQ is involved in the process of cellular respiration and helps support the production of adenosine triphosphate (ATP), the cell's primary energy currency.
Neuroprotective effect
Some studies suggest that PQQ may have neuroprotective effects. It has been studied for its potential role in promoting cognitive function and preventing neurodegenerative diseases.
cardiometabolic health
PQQ is currently being studied for its potential benefits on cardiometabolic health. Some studies suggest it may have a positive impact on factors such as blood pressure, cholesterol levels, and glucose metabolism.
food source
PQQ is found in some foods, especially in trace amounts. Foods containing PQQ include
- fermented soybeans
- Green pepper
- kiwi
- coriander
- Tea
- pawpaw
- spinach
- celery
supplements
When taken as a supplement, PQQ is classified as a nootropic. Some people choose to take PQQ supplements to potentially increase their intake beyond what they get from dietary sources. PQQ supplements are usually sold in capsule or softgel form . Most of the research has been conducted only in animal studies, and there is little evidence that supplement forms provide any meaningful health benefits. These supplements are usually powdered and made through a bacterial fermentation process. It's unclear whether PQQ has side effects.
Research and Health Statements
While research into the potential health benefits of PQQ is ongoing, it is important to note that not all health claims related to PQQ have been conclusively proven. Research is still evolving and more research is needed to fully understand the extent of its effects.