What is virginiamycin?
Virginiamycin is a streptomycin antibiotic similar to pristine and quinupristin/dalfopristin. It is a combination of original mycin IIA (virginiamycin M1) and virginiamycin S1. Virginiamycin is used in the fuel ethanol industry to prevent microbial contamination. It is also used in agriculture, especially in livestock, to accelerate the growth of animals and to prevent and treat infections. Antibiotics can also save young pigs up to 30% in feed costs, but the savings taper off as the pigs age, according to a USDA study.
CAS number 21411-53-0
Mechanism
Virginiamycin M1 is a macrolide antibiotic that acts synergistically with structurally unrelated cyclic depsipeptides, commonly known as virginiamycin B (ostreogrycin B or streptogramin B) and S, to inhibit peptide elongation. long. This is achieved by blocking the formation of peptide bonds between the growing peptide chain (peptidyl-tRNA) and the aminoacyl-tRNA attached to the 50S ribosome. Virginiamycin M1 has been shown to be highly active against Gram-positive bacteria, particularly methicillin-resistant Staphylococcus aureus.
synonyms
- virginiamycin
- C49WS9N75L
- Antibiotic No. 899
- Stapyocine
- Virgimycin
- Virginiamicina
- Virginia mycine
- Virginiamycinum
- 234-244-6
- Eskalin 500
- Eskalin V
- Patricin
- SKF 7988
- SKF-7988
- Staffac
- Staffac 20
- Staffac 50
- Staffac 500
- Staphylomycine
- V-Max
- V-Max 50
- Vernamycin
- Virgimycine
- CHEBI:87209
- D06AX10
- DTXSID40880080
- EINECS 234-244-6
- Eskalin (Vet)
- HSDB 7033
Other identification codes
- CAS 11006-76-1
- EC No. 234-244-6
- UNII C49WS9N75L
- NCI thesaurus code C937
