過量咖啡因的副作用

Coffee and tea are very healthy drinks.

Most types contain caffeine, a substance that can improve your mood, metabolism, and mental and physical performance.

Research also shows that it is safe for most people when consumed in small to moderate amounts.

However, high doses of caffeine can have unpleasant or even dangerous side effects.

Research shows that your genes have a significant impact on your tolerance. Some people can consume more caffeine than others without negative effects .

Additionally, people who are not accustomed to caffeine may experience symptoms after consuming what is typically considered a moderate dose of caffeine .

anxiety

Caffeine is known to increase alertness.

It works by blocking the effects of adenosine, a brain chemical that makes you feel tired. At the same time, it triggers the release of adrenaline, the "fight or flight" hormone associated with increased energy.

However, at higher doses, these effects may become more pronounced, causing anxiety and nervousness.

In fact, caffeine-induced anxiety is one of four caffeine-related syndromes listed in the Diagnostic and Statistical Manual of Mental Disorders (DSM), published by the American Psychiatric Association.

Extremely high doses of 1,000 mg or more per day have been reported to cause jitteriness, restlessness and similar symptoms in most people, while even moderate intakes may cause similar effects in caffeine-sensitive people.

Additionally, moderate doses have been shown to cause shortness of breath and increase stress levels when consumed in one sitting.

One study of 25 healthy men found that those who consumed about 300 milligrams of caffeine experienced more than twice as much stress as those who took a placebo.

Interestingly, cortisol levels were similar between regular and infrequent caffeine drinkers, suggesting that this compound may have the same impact on stress levels whether you're a habitual caffeine drinker or not.

However, these results are preliminary.

The caffeine content of coffee varies widely. For reference, a "grande" cup of coffee from Starbucks contains about 330 milligrams of caffeine.

If you find that you often feel jittery or jittery, it's a good idea to check your caffeine intake and cut back.

Insomnia

Caffeine's ability to help people stay awake is one of its most prized qualities.

On the other hand, too much caffeine can make it difficult to get enough restorative sleep.

Studies have found that higher caffeine intake appears to increase the time it takes to fall asleep. It may also reduce total sleep time, especially in older adults.

In contrast, low or moderate amounts of caffeine do not appear to have much of an impact on the sleep of those who are considered "good sleepers" or even those who self-report insomnia.

If you underestimate how much caffeine you consume, you may not realize that too much caffeine can disrupt your sleep.

While coffee and tea are the most concentrated sources of caffeine, caffeine is also found in soda, cocoa, energy drinks, and several medications.

For example, a cup of energy drink may contain up to 350 mg of caffeine, and some energy drinks contain up to 505 mg of caffeine per can.

Importantly, the amount of caffeine you can consume without disrupting your sleep depends on your genetics and other factors.

Additionally, caffeine consumed later in the day may interfere with sleep, as its effects may take several hours to wear off.

Research shows that while caffeine remains in your system for an average of five hours, that time period can vary from one and a half to nine hours, depending on the individual.

One study examined how the timing of caffeine intake affects sleep. Researchers asked 12 healthy adults to take 400 milligrams of caffeine 6 hours before bed, 3 hours before bed, or just before bed.

The time it took for all three groups to fall asleep and the amount of time they were awake during the night increased significantly.

These results suggest that paying attention to the amount and timing of caffeine intake is important to optimize sleep.

digestive problems

Many people find that drinking a cup of coffee in the morning helps with bowel movement.

The laxative effect of coffee is attributed to the release of gastrin, a hormone produced by the stomach that speeds up the activity of the colon. Additionally, decaf coffee has been shown to produce a similar response.

Given this effect, it's not surprising that large doses of caffeine may cause loose stools or even diarrhea in some people.

Although coffee has been thought to cause stomach ulcers for years, a large study of more than 8,000 people found no link.

On the other hand, some studies suggest that caffeinated drinks may worsen gastroesophageal reflux (GERD) in some people. This seems to be especially true with coffee.

In one small study, when five healthy adults drank caffeinated water, they experienced muscle relaxation that prevents stomach contents from moving up into the throat—a sign of gastroesophageal reflux.

Since coffee can have a significant impact on digestion, you may want to cut back on the amount you drink or switch to tea if you experience any problems.

muscle breakdown

Rhabdomyolysis is a very serious disease in which damaged muscle fibers can enter the bloodstream, causing kidney failure and other problems.

Common causes of rhabdomyolysis include trauma, infection, drug abuse, muscle strain, and snake or insect bites.

Additionally, there have been several reports of rhabdomyolysis associated with excessive caffeine ingestion, although this is relatively rare.

In one case, a woman experienced nausea, vomiting, and dark urine after drinking 32 ounces (1 liter) of coffee containing approximately 565 mg of caffeine. Fortunately, she recovered with medication and fluids.

Importantly, this is a reason to consume large amounts of caffeine in a short period of time, especially for those who are not used to it or are highly sensitive to its effects.

To reduce the risk of rhabdomyolysis, it's best to limit your daily caffeine intake to around 400 milligrams, unless you're used to consuming more.

addiction

Although caffeine has many health benefits, there is no denying that it can be addictive.

A detailed review suggests that although caffeine triggers certain brain chemicals like cocaine and amphetamines, it does not cause classic addiction like these drugs.

However, it may cause psychological or physical dependence, especially at high doses.

In one study, 16 people who usually consumed high, moderate or no caffeine took a single-word test after going caffeine-free overnight. Only high caffeine users showed a bias toward caffeine-related words and had a strong craving for caffeine.

Additionally, the frequency of caffeine intake appears to have an impact on dependence.

In another study, 213 caffeine users completed questionnaires after 16 hours without coffee. Daily users experienced greater increases in headaches, fatigue, and other withdrawal symptoms than non-daily users.

Although this compound does not appear to cause true addiction, if you regularly drink large amounts of coffee or other caffeinated beverages, there is a good chance that you may become dependent on its effects.

hypertension

Overall, caffeine does not appear to increase the risk of heart disease or stroke in most people.

However, multiple studies have shown that it can increase blood pressure due to its stimulating effects on the nervous system.

Elevated blood pressure is a risk factor for heart attacks and strokes because, over time, it can damage arteries and restrict blood flow to the heart and brain.

Fortunately, caffeine's effects on blood pressure appear to be temporary. Additionally, it seems to have the greatest impact on people who are not used to eating it.

Studies have also shown that high amounts of caffeine consumed during exercise can increase blood pressure in both healthy people and people with mildly elevated blood pressure.

Therefore, it's important to pay attention to your caffeine dosage and timing, especially if you already have high blood pressure.

Heart rate too fast

The stimulating effects of high caffeine intake may cause your heart to beat faster.

It can also cause a change in heart rate called atrial fibrillation, which has been reported in young people who drink energy drinks containing extremely high doses of caffeine.

In one case study, a woman developed a rapid heart rate, kidney failure and other serious health problems after taking large amounts of caffeine powder and pills in an attempted suicide.

However, this effect doesn't seem to happen to everyone. In fact, even some people with heart disease may be able to tolerate large amounts of caffeine without any side effects.

In a controlled study, when 51 heart failure patients took 100 mg of caffeine every hour for 5 hours, their heart rates and rhythms remained normal.

Regardless of study results, if you notice any changes in your heart rate or rhythm after drinking caffeinated beverages, consider reducing your intake.

fatigue

Coffee, tea, and other caffeinated beverages are known to increase energy levels.

However, they can also have the opposite effect, causing fatigue to rebound after the caffeine leaves your system.

A review of 41 studies found that although caffeinated energy drinks increased alertness and improved mood for several hours, participants tended to be more tired than usual the next day.

To maximize the energy benefits of caffeine and avoid a fatigue rebound, consume it in moderation rather than large amounts.

Frequent urination and urgency

Increased urination is a common side effect of high caffeine intake because of the irritating effects of this compound on the bladder.

You may have noticed that when you drink more coffee or tea than usual, you need to urinate more often.

Most studies examining the compound's effects on frequent urination have focused on older adults and people with overactive bladders or urinary incontinence.

In one study, 12 young to middle-aged people with overactive bladder who consumed 2 mg of caffeine per pound of body weight per day (4.5 mg/kg) experienced significant increases in frequency and urgency of urination.

For a person weighing 150 pounds (68 kg), this is equivalent to about 300 milligrams of caffeine per day.

Additionally, high intake may increase the likelihood of urinary incontinence in people with healthy bladders.

One large study examined the effects of high amounts of caffeine on incontinence in more than 65,000 women who were not incontinent.

People who consumed more than 450 mg per day had a significantly increased risk of incontinence compared with those who consumed less than 150 mg per day.

If you drink a lot of caffeinated drinks and feel like you're urinating more frequently or more urgently than you should, it might be a good idea to reduce your intake and see if your symptoms improve.

generalize

Low to moderate caffeine intake appears to be beneficial to the health of many people.

On the other hand, very high doses may cause side effects, interfere with daily life, and may even lead to serious health problems.

Although responses vary from person to person, the effects of high intakes suggest that more is not necessarily better.

To get the benefits of caffeine without the adverse effects, make an honest assessment of your sleep, energy levels, and other factors that may be affected, and reduce your intake if needed.

Review

All comments are moderated before being published

HealthyPIG Magazine

View all
牛肉與腸道微生態:人體點樣反應?

牛肉與腸道微生態:人體點樣反應?

牛肉進入身體之後會發生咩事? 食牛肉之後,身體會進入「高蛋白消化模式」: 胃部階段:胃酸(pH約2)與胃蛋白酶一齊將牛肉蛋白質分解成小分子胺基酸鏈。此時釋放「胃泌素(gastrin)」促進更多酸及酶分泌。 小腸階段:十二指腸接收食糜後,胰臟釋出胰蛋白酶、脂肪酶,肝臟釋出膽汁乳化脂肪。 ...
從嗜睡症、慢脈搏到米諾地爾 (Minoxidil) 的全身動力學

從嗜睡症、慢脈搏到米諾地爾 (Minoxidil) 的全身動力學

當身體進入「慢模式」——嗜睡症與自律神經的連結 嗜睡症(Narcolepsy)是一種大腦覺醒系統的紊亂,患者在日間容易突然進入睡眠狀態。但其實,嗜睡症不止影響「睡眠」,還會影響全身的 自律神經系統 (Autonomic Nervous System)。 自律神經負責調節: 心跳快慢(交感與...
降血壓,唔一定靠藥!了解身體機制,從生活開始調節

降血壓,唔一定靠藥!了解身體機制,從生活開始調節

高血壓唔係「年紀大」嘅專利,愈來愈多年輕人都有血壓偏高。其實,血壓高並非只係「壓力大」咁簡單,而係整個身體系統出問題:心臟、血管、腎臟、神經、荷爾蒙都有份參與。

原糖 vs 紅糖 vs 白糖:哪一種更健康?

原糖 vs 紅糖 vs 白糖:哪一種更健康?

日常生活中,我們常見的糖有「原糖」、「紅糖」與「白糖」。三者外觀、味道甚至用途都略有不同,但在營養與健康層面上又有幾大差異。本文將帶你深入了解它們的製作方式、特性與對身體的影響。

籃球係有氧運動嗎?— 一文睇清有氧同無氧運動嘅分別、好處同平衡之道

籃球係有氧運動嗎?— 一文睇清有氧同無氧運動嘅分別、好處同平衡之道

籃球係全球最受歡迎嘅運動之一,無論係街場隨意投籃、定係正式比賽,都可以幫助身體活動。但你有冇諗過,籃球到底屬於「有氧運動」定「無氧運動」?兩者又有咩分別?點樣玩先至最有益身體?

本文會同你用簡單角度拆解「有氧」同「無氧」嘅概念,並講解籃球點樣同時結合兩者,最後再分享點樣令你嘅籃球運動更健康、更有效。

男士禿頭對策:了解雄性禿與5%米諾地爾(Minoxidil)生髮原理

男士禿頭對策:了解雄性禿與5%米諾地爾(Minoxidil)生髮原理

雄性禿是什麼?為何只在頭頂出現? 好多男士年過25歲開始發現頂部頭髮越來越稀疏,但前額線卻似乎仍然正常,這情況其實非常典型。這種情況稱為 雄性禿 (Androgenetic Alopecia),是男性最常見的脫髮原因之一。 主要成因來自兩方面: 遺傳基因:如果父母其中一方有禿頭問題,後代的...
發現死老鼠點處理?

發現死老鼠點處理?

喺屋企、後花園、廚房甚至車房發現一隻「死老鼠」唔係罕見事,但好多屋主第一時間會「嚇親」或者「即刻掃走」。其實咁樣反而危險!
死鼠可能帶有漢他病毒、鈎端螺旋體病、沙門氏菌等病原體,一旦處理唔當,吸入塵埃或者接觸體液,都可能感染疾病。以下教你一套澳洲、香港、台灣都適用嘅安全清理步驟。

老鼠與大鼠的衛生影響:對人體與家居健康的真正威脅

老鼠與大鼠的衛生影響:對人體與家居健康的真正威脅

「老鼠」同「大鼠」雖然都屬於齧齒類,但牠哋對人類健康嘅影響有明顯分別。本文會詳細講解牠哋嘅衛生差異、疾病傳播途徑、同預防方法

無人機醫療配送:低空經濟下的香港新契機

無人機醫療配送:低空經濟下的香港新契機

  無人機醫療配送:低空經濟下的香港新契機 —— 從健康、醫療金融到商業模式的全球比較與啟示 在香港「低空經濟」監管沙盒下,無人機由數碼港跨海至長洲醫院,約 12 公里航線僅需 18–20 分鐘,相比傳統 45–65 分鐘大幅提速。本文聚焦醫療價值、醫療金融回報與商...