什麼是檸檬酸鈣 (E333)?

Calcium citrate is the calcium salt of citric acid.

Calcium citrate is an over-the-counter (OTC) calcium supplement. Calcium is an essential mineral for healthy teeth and bones. It is also important for blood vessel, muscle and nerve health, and supports hormonal function.

Calcium supplements are usually sold as calcium carbonate or calcium citrate. Calcium citrate is easier to absorb than calcium carbonate. Your body doesn't need stomach acid to absorb calcium citrate, which makes it a better choice for people who take heartburn medication or have digestive issues.

Calcium citrate is available in tablet, powder, and gummy forms. It can be taken on an empty stomach. However, it works best when taken with food.

  • CAS No. 813-94-5
  • EC number 212-391-7
  • E No. E333

Calcium citrate uses

Calcium is an important mineral that supports multiple systems throughout the body. You must maintain adequate calcium levels for your heart, nervous system, and muscles to function properly.

Calcium is probably best known for building strong bones. But beyond bones, possible benefits of calcium supplementation include lowering the risk of cancer, heart disease, preeclampsia and metabolic syndrome. It can also help some people maintain a healthy weight. Research supports some of these uses more than others.

bone health

Because calcium's role in building healthy, strong bones is well known, some studies have focused on whether calcium supplements can prevent age-related loss of bone mineral density (BMD) and fractures. Unfortunately, the results of this study are mixed.

For example, one study used data from the National Health and Nutrition Examination Survey to evaluate the association between dietary calcium intake and BMD in older adults. Studies have found that higher dietary calcium intake is associated with greater BMD in the lumbar spine (the vertebrae of the lower spine). The researchers found that this benefit was only seen in women, but not in men.

Another study of calcium intake and bone loss in osteopenic postmenopausal people found no effect on bone loss.

cancer

Due to the protective effect of calcium on cells. Overall, however, the findings are mixed.

One study evaluated the effects of calcium and vitamin D supplements on cancer rates in older women. There was no significant reduction in cancer risk after four years compared with placebo.

heart disease

Calcium has the ability to reduce lipid absorption, with mixed results, with some studies showing no effect.

Data from a study on calcium intake and hypertension in obese adults. Among adults, researchers found that those with high blood pressure and obesity had a 10% lower calcium intake.

However, one clinical trial found that calcium supplements increased the risk of heart disease by a significant 15% in a healthy postmenopausal population.

other

In addition to the potential health benefits listed above, some people use calcium to:

  • preeclampsia
  • lose weight
  • metabolic syndrome

lack of calcium

Some people may develop a calcium deficiency when their calcium intake falls below recommended levels over time, they have specific risk factors for lower than normal levels, or there is a special reason why they are unable to digest or absorb calcium.

What causes calcium deficiency?

When you don't get enough calcium from external sources, such as food or supplements, or you don't absorb calcium well, your body uses calcium from your bones to maintain blood levels. Over time, taking calcium from your bones can weaken your bones and increase your risk of fractures.

People most at risk of calcium deficiency are postmenopausal people and those who do not eat dairy products.

How do I know if I am calcium deficient?

Calcium deficiencies may require specific laboratory testing by a healthcare provider to properly identify and diagnose. However, certain symptoms and health conditions may indicate a deficiency. These include:

  • reduced bone strength
  • osteoporosis
  • osteopenia
  • fracture
  • rickets in children
  • adult bone disease

For women over 50, a bone density screening is an excellent way to assess the condition of your bones. If you are unsure whether you are meeting your calcium needs, a nutritionist may be able to assist.

What are the side effects of calcium citrate?

Your healthcare provider may recommend that you take calcium citrate to maintain bone health. However, there may be potential side effects from consuming supplements such as calcium citrate. These side effects can be common or serious.

Common side effects

Common side effects of calcium include:

  • gas
  • abdominal bloating
  • constipate

Most of the time, you can reduce symptoms by taking smaller doses throughout the day or taking the supplement with meals.

serious side effects

Rarely, calcium supplementation can cause more serious conditions, including:

  • heart disease
  • Gastrointestinal diseases
  • kidney stones
  • age-related macular degeneration
  • metabolic syndrome

There is controversy about the benefits of calcium supplements. Some researchers suspect that calcium supplements are not effective in reducing fractures and may cause other problems.

Precaution

If you have a history of kidney disease, kidney stones, cancer, high blood calcium, or parathyroid disease, talk to your healthcare provider before taking calcium citrate supplements.

In addition, calcium supplements may interact with certain medications, including:

  • Dovato, Tivicay (dolutegravir)
  • Synthroid, Levoxyl (levothyroxine)
  • Eskalith, Lithobid (lithium)
  • Quinolone antibiotics, such as Cipro (ciprofloxacin), Factive (gemifloxacin), and Avelox (moxifloxacin)

Be sure to discuss calcium citrate supplements with your health care provider and ask your pharmacist if you are unsure about possible interactions.

Dosage: How much calcium should I take?

When it comes to calcium supplements, determining the exact dosage can be confusing. This is because pure calcium (elemental calcium) is mixed with fillers when the supplement pills are made.

For example, calcium carbonate is composed of 60% carbonate and 40% elemental calcium. Technically speaking, calcium citrate contains only 21% calcium. 10 Read the label to find out how much pure calcium is in each pill.

The recommended dietary allowance (RDA) for calcium is as follows:

  • 200 mg: birth to 6 months
  • 260 mg: 7 to 12 months
  • 700 mg: 1 to 3 years
  • 1,000 mg: 4 to 8 years
  • 1,300 mg: 9 to 18 years
  • 1,000 mg: Everyone ages 19 to 50; Men 51-70
  • 1,200 mg: Women over 50 and men over 70

What happens if I take too much?

As with any dietary supplement, taking too much calcium may do more harm than good. Therefore, only take supplements after you know you are not getting enough from food and drinks and consult your healthcare provider.

To avoid toxicity, pay attention to the appropriate recommended dosage (as mentioned above) and keep the upper limit in mind. For calcium, the Food and Nutrition Board has established safe upper limits as follows:

  • 0-6 months: 1,000 mg
  • 7-12 months: 1,500 mg
  • 1–8 years: 2,500 mg
  • 9–18 years: 3,000 mg
  • Ages 19–50: 2,500 mg
  • Ages 51 and older: 2,000 mg

If you consume more than this amount or more than your healthcare provider recommends, you may need to seek medical assistance.

How to Store Calcium Citrate

Store calcium in a cool, dry place. Keep it away from direct sunlight. Throw away after one year or as directed on packaging.

Calcium sources and precautions

Calcium is vital for people of all ages. Children and teenagers' bones are still forming and they should be careful to get enough calcium. Sitting down with a healthcare provider to review your eating habits can help determine if you're getting enough.

Calcium is easily available in food. Food sources are optimal because they are best absorbed in the body. However, supplements can also help meet daily needs when you cannot meet your needs through food sources alone.

calcium citrate supplement citric acid

Supplements typically contain 200-300 mg or 500-600 mg when combined with vitamin D. 10 Calcium citrate can be taken at any time of the day on a full or empty stomach.
Calcium absorption is highest at lower doses of calcium. For example, you will absorb about 36% of a 300 mg dose, but only 28% of a 1,000 mg dose.

generalize

Calcium is essential for strong bones, teeth and muscles. Calcium citrate supplements can help you meet your recommended daily intake, especially if you have trouble absorbing calcium. For most people, adequate calcium is obtained through food alone. Some people take calcium citrate to maintain bone health and reduce the risk of cancer and heart disease. However, research on these benefits is mixed.

Review

All comments are moderated before being published

HealthyPIG Magazine

View all
無人機醫療配送:低空經濟下的香港新契機

無人機醫療配送:低空經濟下的香港新契機

  無人機醫療配送:低空經濟下的香港新契機 —— 從健康、醫療金融到商業模式的全球比較與啟示 在香港「低空經濟」監管沙盒下,無人機由數碼港跨海至長洲醫院,約 12 公里航線僅需 18–20 分鐘,相比傳統 45–65 分鐘大幅提速。本文聚焦醫療價值、醫療金融回報與商...
醫管局普通科門診改名「家庭醫學門診」——香港基層醫療新里程?

醫管局普通科門診改名「家庭醫學門診」——香港基層醫療新里程?

  基層醫療 家庭醫學 健康政策 醫管局普通科門診改名「家庭醫學門診」:利與弊、國際比較與香港基層醫療的下一步 醫務衞生局宣佈由 2025 年 10 月 11 日起,將「普通科門診」與「家庭醫學專科門診」統一命名為「家庭醫學門診服務」,74 間普通科門診...
基孔肯雅熱:被伊蚊叮咬後的劇痛病毒 — 病毒、傳播、症狀與防治全解析

基孔肯雅熱:被伊蚊叮咬後的劇痛病毒 — 病毒、傳播、症狀與防治全解析

什麼是基孔肯雅熱? 基孔肯雅熱(Chikungunya Fever)是一種由**基孔肯雅病毒(Chikungunya virus, CHIKV)**引起的急性傳染病,屬於 Togaviridae 家族 Alphavirus 屬。這種病毒最早於 1952 年在坦桑尼亞被發現,其名稱來自當地馬孔德...
登革熱:全球爆發中的熱帶威脅與防護全解析

登革熱:全球爆發中的熱帶威脅與防護全解析

登革熱係乜嘢? 登革熱(Dengue fever)係一種由登革熱病毒(Dengue virus)引起嘅急性傳染病,主要經由伊蚊(Aedes mosquito)叮咬傳播,特別係白紋伊蚊(Aedes albopictus)同埃及伊蚊(Aedes aegypti)。呢啲蚊喺日間最活躍,因此唔似瘧疾嗰...
流感點樣會引致腦病變、心肌炎同休克?——從「感冒」變成致命風暴

流感點樣會引致腦病變、心肌炎同休克?——從「感冒」變成致命風暴

近排有新聞報導,一名原本健康嘅中學生感染乙型流感(Influenza B)之後,出現腦病變、心肌炎同休克,情況危殆。好多家長都會問:「流感唔就係普通感冒?點解可以嚴重到影響腦同心臟?」其實,流感背後嘅機制比我哋想像中複雜得多。 一、流感病毒唔止攻擊呼吸道 流感病毒(包括甲型同乙型)主要透過飛...
牛骨湯食譜大全|Instant Pot 壓力煲 & 傳統老火湯版本

牛骨湯食譜大全|Instant Pot 壓力煲 & 傳統老火湯版本

牛骨湯食譜係香港家庭常見嘅煲湯之一,牛骨湯香濃滋補,配合中藥材更具養生功效。本文介紹肉骨類選擇、牛骨湯建議配搭、常見中藥材分類,以及Instant Pot壓力煲與傳統老火湯版本食譜,並引用科學研究支持。
澳洲飲用水發現「食腦變形蟲」:全球風險與地區對策(含各國/各州實用指南)

澳洲飲用水發現「食腦變形蟲」:全球風險與地區對策(含各國/各州實用指南)

澳洲飲用水發現「食腦變形蟲」:全球風險與地區對策(含各國/各州實用指南) 澳洲飲用水發現「食腦變形蟲」:全球風險與地區對策(含各國/各州實用指南) 重點:事件本身不代表飲水會感染;主要風險來自水經鼻腔進入。 目錄 ...
如何判斷雞翅是否變壞?

如何判斷雞翅是否變壞?

重點摘要 雞翅會變質嗎? 如何判斷雞翅是否變壞? 過期雞翅還能食嗎? 雞翅可存放多久? 如何儲存雞翅? 雞翅可以冷凍嗎? 結論 雞翅會變質嗎? 會。皮脂較多、表面不潔或溫度過高時,細菌繁殖更快。 如何判斷雞翅是否變壞? 外觀:皮色發黃、出黑斑或血水。 觸感:表面黏滑、軟爛。 氣...
如何判斷雞蛋是否變壞?

如何判斷雞蛋是否變壞?

重點摘要 雞蛋會變質嗎? 如何判斷雞蛋是否變壞? 過期雞蛋還能食嗎? 雞蛋可存放多久? 如何儲存雞蛋? 雞蛋可以冷凍嗎? 結論 雞蛋會變質嗎? 會。殼面有微孔,溫差及濕度變化會令細菌入侵。 如何判斷雞蛋是否變壞? 水測:沉底=較新鮮;浮起=多半變壞。 打開觀察:蛋白渾濁水樣、蛋黃...