糖尿病視網膜病變:原因、症狀、治療

Early symptoms: None
Later symptoms: loss of central vision, blurred or wavy central vision, drusen.

Diabetic retinopathy (DR) is a common complication of diabetes. It is the leading cause of blindness among adults in the United States. It is characterized by progressive damage to blood vessels in the retina, the light-sensitive tissue at the back of the eye that is necessary for good vision. The progression of DR is divided into four stages:

  • Mild nonproliferative retinopathy (microaneurysm)
  • Moderate nonproliferative retinopathy (occlusion of certain retinal blood vessels)
  • Severe non-proliferative retinopathy (more blood vessels are blocked, resulting in insufficient blood supply to the retina, resulting in the growth of new blood vessels)
  • Proliferative retinopathy (most advanced stage).

The risk of DR can be reduced through disease management, including good control of blood sugar, blood pressure, and dyslipidemia. Early diagnosis and prompt treatment of DR can reduce the risk of vision loss; however, up to 50% of patients do not receive eye examinations or are diagnosed too late for treatment to be effective. It is the leading cause of blindness among working-age adults aged 20-74 years in the United States. An estimated 4.1 million and 899,000 Americans have retinopathy and sight-threatening retinopathy, respectively.

Two stages of diabetic eye disease

Diabetic eye disease has two main stages.

NPDR (non-proliferative diabetic retinopathy)

This is the early stage of diabetic eye disease. Many people with diabetes have this condition.

In NPDR, tiny blood vessels leak, causing the retina to swell. When the macula swells, it is called macular edema. This is the most common cause of vision loss in people with diabetes.

Additionally, with NPDR, blood vessels in the retina may close. This is called macular ischemia . When this happens, blood cannot reach the macula. Sometimes, tiny particles called exudates form in the retina. These can also affect your vision.

If you have NPDR, your vision becomes blurry.

PDR (proliferative diabetic retinopathy)

PDR is a more advanced stage of diabetic eye disease. This happens when the retina begins to grow new blood vessels. This is called neovascularization. These fragile new blood vessels often leak into the vitreous. If there is just a little bit of bleeding, you may see some black floaters. If the bleeding is excessive, it may block all vision.

These new blood vessels can form scar tissue. Scar tissue may cause problems in the macula or lead to retinal detachment.

PDR is so severe that it can steal your central vision and peripheral side vision.

What happens when you have diabetic retinopathy?

You may have diabetic retinopathy and not know it. This is because it often has no symptoms in its early stages. As diabetic retinopathy worsens, you may notice the following symptoms:

  • Seeing that the number of patients with floaters is increasing,
  • blurred vision,
  • Vision sometimes changes from blurry to clear,
  • Seeing blank or dark areas in your field of vision,
  • Poor night vision, and
  • Notice colors appearing faded or faded
  • Loss of vision.

Diabetic retinopathy symptoms usually affect both eyes.

Diabetic Retinopathy Diagnosis

Place drops into your eyes to dilate your pupils. This allows your eye doctor to look inside your eye through special lenses.

Your doctor may perform an optical coherence tomography (OCT) scan to take a closer look at the retina. The machine scans the retina and provides detailed images of its thickness. This helps your doctor detect and measure macular swelling.

Fluorescein angiography, or OCT angiography, helps your doctor understand the condition of the blood vessels in the retina. Fluorescent angiography uses a yellow dye called luciferin, which is injected into a vein (usually in the arm). The dye travels through your blood vessels. As the dye passes through the retinal blood vessels, a special camera takes pictures of the retina. This can show if there are blockages in the blood vessels or fluid leakage. It also shows whether there are abnormal blood vessel growths. OCT angiography is a newer technology that does not require dye to view blood vessels.

Can diabetic retinopathy disappear?

Your treatment depends on what your eye doctor sees in your eye. Treatment options may include:

medical control

Controlling blood sugar and blood pressure can prevent vision loss. Carefully follow the diet recommended by your nutritionist. Take the medicines prescribed for you by your diabetes doctor. Sometimes, good sugar control can even restore some of your vision. Controlling blood pressure keeps the blood vessels in your eyes healthy.

drug

One type of drug is called an anti-VEGF drug. These include Avastin, Eylea and Lucentis. Anti-VEGF drugs can help reduce macular swelling, slow vision loss, and may improve vision. This medicine is given by injection (injection) into the eye. Steroid medications are another option for reducing macular swelling. This can also be done by injection into the eye. Your doctor will advise you on how many injections you need over time.

laser surgery

Laser surgery can be used to help seal leaky blood vessels. This can reduce retinal swelling. Laser surgery can also help shrink blood vessels and prevent them from growing again. Sometimes more than one treatment is needed.

vitrectomy

If you have advanced PDR, your eye doctor may recommend a surgery called vitrectomy. The ophthalmologist removes vitreous gel and blood from leaky blood vessels in the back of the eye. This allows the light to focus correctly on the retina again. Scar tissue from the retina may also be removed.

5 Ways to Prevent Vision Loss from Diabetic Retinopathy

  • If you have diabetes, talk with your primary care doctor about how to control your blood sugar. High blood sugar can damage retinal blood vessels. This can lead to vision loss.
  • Do you have high blood pressure or kidney problems? Ask your doctor about ways to manage and treat these problems.
  • Visit your eye doctor regularly for dilated eye exams. Diabetic retinopathy may be detected before you notice any vision problems.
  • If you notice changes in vision in one or both eyes, call your eye doctor immediately.
  • Get treatment for diabetic retinopathy as soon as possible. This is the best way to prevent vision loss.

Do you have diabetes and need an eye exam?

Changes in blood sugar levels can affect your vision. Make sure your blood sugar is under control at least a week before your eye exam. Glasses work best when worn when your blood sugar levels are stable!

Review

All comments are moderated before being published

HealthyPIG Magazine

View all
經痛治療點解咁多年都冇突破?最新方法、本地現況與未來方向

經痛治療點解咁多年都冇突破?最新方法、本地現況與未來方向

幾乎一半嘅世界人口,每個月都要面對一次——月經同經痛。由青春期到更年期,呢段時間長達三十幾年。雖然經痛唔係致命疾病,但對好多女性嚟講,每個月都係一次痛苦嘅循環,影響工作、學業同生活質素 [1]。咁問題嚟喇:點解咁多年嚟,經痛治療仲係停留喺熱水袋同布洛芬(ibuprofen)?

Celecoxib(西樂葆)介紹 — 藥理、歷史背景與臨床試驗

Celecoxib(西樂葆)介紹 — 藥理、歷史背景與臨床試驗

1. 藥物簡介與臨床用途 Celecoxib(商品名 Celebrex 等)係一種選擇性 COX-2 抑制劑,屬非類固醇抗炎藥(NSAID)。COX-2 喺炎症反應中會誘導前列腺素生成,從而引發疼痛及發炎;而 Celecoxib 有效抑制 COX-2,但對 COX-1 影響較少,因此相對常見 ...
用粟粉醃肉有乜科學根據?揭開中菜「滑肉」嘅秘密

用粟粉醃肉有乜科學根據?揭開中菜「滑肉」嘅秘密

前言:點解中餐炒肉咁滑? 好多香港人炒肉嘅時候都會發現,餐廳啲雞絲牛柳炒出嚟特別滑溜、唔鞋口。呢個秘密,唔喺高級食材,而係一個平凡但強大嘅材料——粟粉(Cornstarch)。 呢種技巧叫做**「走油前醃」或「滑油醃肉法」(Velveting)**,係中餐獨有技術之一,主要靠粟粉、蛋白、調味料...
咩係三價鐵(Fe³⁺)同二價鐵(Fe²⁺)?

咩係三價鐵(Fe³⁺)同二價鐵(Fe²⁺)?

當我哋講「鐵質」時,唔止係話有冇攝取足夠,而係講緊鐵喺人體內唔同形態(尤其係三價鐵 Fe³⁺ 同二價鐵 Fe²⁺)點樣被吸收、轉化、運輸同儲存,呢啲都深深影響生物可利用率

全面解構低鐵原因、病理機制及影響

全面解構低鐵原因、病理機制及影響

低鐵唔止係營養問題,仲可能係身體慢性警號

鐵質(iron)係人體不可或缺嘅微量元素,主要負責攜帶氧氣嘅血紅素(hemoglobin)製造、能量代謝、免疫調節等。當鐵質長期攝取不足、吸收差、或失去過多,就會導致「低鐵」(iron deficiency)甚至發展成「缺鐵性貧血」(iron deficiency anemia)。本文將從臨床醫學與分子生理角度,深入探討低鐵嘅成因、病理機制、生物轉化過程,以及其對人體造成嘅連鎖影響。

Obefazimod(ABX464):潰瘍性結腸炎新藥研究、作用機制與研發進展

Obefazimod(ABX464):潰瘍性結腸炎新藥研究、作用機制與研發進展

Obefazimod(又名 ABX464)係由法國生物科技公司 Abivax 開發嘅口服小分子創新藥,目標治療慢性發炎性腸道疾病(IBD),特別係潰瘍性結腸炎(UC)同克羅恩氏病(CD)患者。

夢遺係唔係一定關性事?

夢遺係唔係一定關性事?

夢遺,即係在無意識之下於睡眠中射精,係一種常見於青春期男生甚至成年男性身上的自然生理現象。夢遺唔等於一定發生性夢,也唔等於有性慾過強。它與睡眠週期中快速動眼期(REM sleep)嘅勃起模式有關,亦可能反映正常的荷爾蒙波動及精液排出節律。 咩係夢遺? 夢遺(nocturnal emission...
唔凍都會打冷震?

唔凍都會打冷震?

打冷震(shivering)唔一定因為天氣凍,喺情緒波動、發燒初期、焦慮、緊張等情況下都可以出現。打冷震係一種由大腦下視丘控制嘅「非意識性肌肉收縮」,目的係維持或調節核心體溫或應對突發壓力。了解打冷震背後嘅神經與體溫調節原理,可以幫我哋區分「正常生理反應」同「潛在疾病警號」。 打冷震係乜回事...
一緊張就流手汗?

一緊張就流手汗?

手掌汗腺主要受交感神經系統控制。當人面對壓力、驚訝、社交場合等刺激時,大腦會啟動「戰鬥或逃跑反應」,促使手掌、腳底等部位產生明顯出汗。這種情況屬於精神性出汗,與溫度無直接關係,係身體對外在壓力的自然反應。