Rinvoq ® Upadacitinib is used to treat certain types of arthritis (such as psoriatic arthritis, rheumatoid arthritis, axial spondyloarthritis). It helps reduce joint pain, tenderness and swelling. Upadacitinib is also used to treat a skin condition called atopic dermatitis ( eczema) . It reduces skin swelling, itching and redness. This medication may also be used to treat certain intestinal conditions (Crohn's disease, ulcerative colitis). It helps relieve symptoms such as diarrhea and stomach pain.
How to use Rinvoq
Read the Medication Guide and Patient Information Leaflet (if available) provided by your pharmacist before you start taking upadacitinib and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take this medication by mouth with or without food as directed by your doctor, usually once daily. Do not crush, chew, or split tablets. Doing so releases all the medication immediately, increasing the risk of side effects.
Use this medication regularly to get the most benefit. To help you remember, take it at the same time every day.
The dosage is based on your medical condition, response to treatment, age, and other medications you may be taking. Be sure to tell your doctor and pharmacist of all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Do not increase your dose or use this medication more often or for longer than prescribed. Your condition will not improve faster, and your risk of side effects will increase.
Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you can do so safely. Grapefruit can increase the chance of side effects from this drug. Consult your physician or pharmacist for more details.
Tell your doctor if your condition does not get better or gets worse.
side effect
See also the warning section.
Nausea or headache may occur. If these effects persist or get worse, tell your doctor or pharmacist promptly.
You may rarely see pills or parts of pills in your stool. This may occur if you have certain intestinal conditions (eg, ileostomy, colostomy). If you find tablets in your stool, tell your doctor right away.
People using this medication may have serious side effects. However, you have been prescribed this medication because your doctor has judged that the benefit to you is greater than the risk of side effects. Careful monitoring by your doctor may reduce your risk.
Tell your doctor right away if you have any serious side effects, including: symptoms of anemia (such as unusual tiredness, pale skin, fast heartbeat), symptoms of liver disease (such as persistent nausea/vomiting, loss of appetite), stomach/abdominal pain, eye/ yellowing of the skin, dark urine), signs of severe tearing of the stomach or intestinal wall (such as persistent severe stomach/abdominal pain, fever, severe dizziness, fainting, severe nausea/vomiting).
Get medical help right away if you have any very serious side effects, including: Sudden changes in vision (such as blurred vision, seeing flashes of light).
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Precaution
See also the warning section.
Before taking upadacitinib, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients that may cause allergic reactions or other problems. Ask your pharmacist for more details.
kidney disease.
Upadatinib may make you more susceptible to infections or may make a current infection more serious. Stay away from anyone who has an infection that may be easily spread (e.g., chickenpox, COVID-19, measles, influenza). Consult your physician if you have been exposed to an infection or for more details.
Before having any immunizations/vaccination, tell your health care professional that you are using upadacitinib. Avoid contact with people who have recently received a live vaccine (such as a flu shot inhaled through the nose).
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Older adults may be at greater risk of side effects when using this medication.
Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while using upadacitinib. Upapatinib may harm your unborn baby. Your doctor should order a pregnancy test before you start taking this medication. Ask about reliable forms of birth control while you are using this medicine and for 4 weeks after your last dose. If you are pregnant, discuss the risks and benefits of this medication with your doctor right away.
It is not known whether this medication passes into breast milk. Because of the possible risk to the baby, breastfeeding is not recommended while using this medication and for 6 days after the last dose. Please consult your doctor before breastfeeding.
Please consult your pharmacist or doctor.
interactive
See also the How to use section.
Drug interactions may change how medications work or increase the risk of serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicine without your doctor's approval.
Other drugs may affect the removal of upadacitinib from the body, which may affect how upadacitinib works. Examples include rifampicin, phenytoin, and others.
