Acetyl-p-nitrophenyl sulfanilamide (also known as acetyl-p-nitrophenyl sulfanilamide, or APNS) is an organic compound used in some drugs and as a synthetic compound in other Intermediates of compounds. It is an important component of some antibiotics, antifungals and anti-inflammatory agents. It comes in the form of a white to off-white crystalline powder that is insoluble in water.
Sulfanitran is a sulfonamide antibiotic used in the poultry industry. It is a component of Novastat, Polystat and Unistat, brands of feed additives used to control Coccidioides spp.
Molecular formula
C14H13N3O5S
Chemical specifications
Chemical Name
(1) Sulfonamide group: acetyl-(p-nitrophenyl)-sulfonamide.
(2) Akrolamide: 2-chloro-4-nitrobenzamide.
Specification
(1) Sulfa drugs meet the following specifications:
(i) Melting point range: 260°C. to 261°C.
(ii) Content (titrated with sodium nitrite): 97% to 100.5%.
(iii) Moisture: not more than 2.0%.
(iv) Molecular weight: 335.34.
(v) Soluble in 0.1N sodium hydroxide, and remains unchanged after acidification.
