食物中的乳酸是好是壞?

What is malic acid?

Malic acid is an alpha hydroxy acid found in some fruits and wine. It is used in food and cosmetics and sometimes as medicine.

Malic acid has a sour taste. When applied to the skin, this helps remove dead skin cells. Its sour taste also helps people with dry mouth produce more saliva. Malic acid is also involved in the Krebs cycle. This is the process the body uses to generate energy. People often use malic acid to treat dry mouth.

It is also used to treat acne, fibromyalgia, fatigue, skin wrinkles, and many other conditions, but there is no good scientific evidence to support these uses. Malic acid is an alpha hydroxy acid. Do not confuse this with other alpha hydroxy acids (AHAs).

Uses of malic acid

Supplement use should be individualized and reviewed by a health care professional (such as a registered dietitian, pharmacist, or health care provider). Here are some of the purported uses of malic acid with varying degrees of scientific evidence.

Skin care

Malic acid is an alpha hydroxy acid said to be a natural exfoliant. It can be used to smooth wrinkles and fine lines, improve skin texture, cleanse pores, and improve overall skin. Because of this, malic acid has been used in a variety of skin care products.

One study found that malic acid helps treat melasma, a common condition characterized by abnormally dark patches of skin. In the study, researchers assigned people with melasma a skin care regimen containing malic acid and vitamin C. At the end of the study, the researchers concluded that using malic acid as a regular part of your skin care regimen could help improve the appearance of melasma.

This study used a combination of malic acid and vitamin C. This means that although the researchers concluded that malic acid was the beneficial ingredient in the study, there is no way of knowing whether the results were due to malic acid alone, vitamin C alone, or a combination of the two.

Kidney stones

In one study, malic acid was found to increase urine pH, thereby reducing the likelihood of kidney stone formation. Researchers concluded that malic acid supplementation may help treat calcium kidney stones.

A review of the importance of a healthy diet in preventing kidney stones suggests pears may be a potential treatment option. According to the review, the malic acid in pears may be used to prevent the formation of kidney stones. This is because malic acid is a precursor to citrate, a compound that inhibits crystal growth in the kidneys.

Fibromyalgia

A preliminary study finds that malic acid combined with magnesium helps reduce pain and tenderness in people with fibromyalgia.

In this small study, researchers gave fibromyalgia patients a placebo or a combination of malate and magnesium. After six months, patients who received the malate/magnesium combination experienced significant improvements in pain and tenderness.

However, because a combination of magnesium and malic acid was used in the study, we don't know which one was responsible for the positive results. There is still a lack of current research on the effectiveness of malic acid in treating fibromyalgia.

Dry mouth

The use of 1% oral malic acid spray has been explored for the treatment of dry mouth.

One study evaluated patients with xerostomia caused by antidepressant medications. Participants were randomly assigned to receive either 1% malic acid spray or a placebo. After two weeks of using the spray as needed, people who used malic acid spray had improved dry mouth symptoms and increased saliva flow.

Another study looking at malic acid to treat dry mouth caused by blood pressure medications had similar results. At the end of the two-week study, participants who used the 1% malic acid spray had less dry mouth and more saliva than those in the placebo group.

Regulatory Reference

1. CANADA INGREDIENT HOTLIST, a list of ingredients restricted for use in cosmetics
- α-Hydroxy acid
2. US FDA Food Additive Status List
- Malic acid, L-malic acid
3. EU-approved food additives
- E296
4. List of designated food additives specified in Article 10 of the Japanese Food Sanitation Law
- DL-malic acid (dl-malic acid)
5. US FDA Generally Recognized as Safe (GRAS) Food Substances (21 CFR 184) [2017]
- § 184.1069 - Malic acid

Safety and Hazards (UN GHS):

1. Harmful if swallowed (H302)
2. Causes skin irritation (H315)
3. Causes severe eye irritation (H319)
4. May cause respiratory tract irritation (H335)

Drug interaction

High blood pressure medications (antihypertensive drugs) interact with malic acid
Malic acid may lower blood pressure. Taking malic acid with blood pressure-lowering medications may cause blood pressure to become too low. Monitor your blood pressure closely.

Dosage: How much malic acid should I take?

Various amounts were used in the studies.

For example, one old fibromyalgia study used a product called Super Malate, which contained 1,200 mg of malic acid along with 300 mg of magnesium hydroxide. Taking it twice daily for six months showed positive results.

Various studies on malic acid for the treatment of dry mouth have used a spray solution containing 1% malic acid.

The right dose for you may depend on the reason you are using malic acid and other factors such as your age, gender, and medical history. Please consult your healthcare provider for individualized dosage recommendations.

What will happen if I take too much malic acid?

Currently, there is no evidence that you can overdose on malic acid. Malic acid is also not considered toxic.

However, research on malic acid is limited, and we have no studies on its long-term use. We also do not have standard dosage information for malic acid.

The report pointed out that malic acid had been considered non-toxic before. Still, it's important to use malic acid exactly as directed to prevent any potential problems.

How to store malic acid

Store malic acid supplements in a cool, dry, well-ventilated area of ​​your home. Be sure to store supplements in the container they were purchased in. Malic acid for external use should be stored in a similar manner.

Discard malic acid supplements and treatments according to the expiration date listed on the package. Keep these and other supplements in a place in your home out of the reach of children or pets.

Similar supplements

Other supplements on the market may have similar effects to malic acid.

Supplements similar to malic acid include:

    • Vitamin C: Vitamin C serum has been found to improve skin pigmentation and melasma. Vitamin C is a natural antioxidant that improves skin pigmentation by disrupting the process of dark spot formation.
    • Magnesium: Like malate, magnesium has been studied for its potential role in preventing kidney stones. Although the evidence is somewhat mixed, magnesium may reduce the crystallization of certain types of kidney stones by inhibiting calcium oxalate. It has also been suggested that magnesium deficiency may be a risk factor for kidney stones.
    • Capsaicin: Capsaicin, the active ingredient in chili peppers, may be beneficial in treating fibromyalgia. One study found that a topical treatment containing 0.075% capsaicin provided short-term improvements in fibromyalgia symptoms such as fatigue and pain.
    • Ginseng: Korean red ginseng, also known as ginseng, may help treat dry mouth. One study reported that dry mouth symptoms improved in women but not men after taking 6 grams of Korean red ginseng for eight weeks. Notably, the most successful women in the study were postmenopausal.

Consult your healthcare provider before taking more than one supplement for the same purpose. It is generally recommended not to mix supplements.

Frequently asked questions

  • What is the richest source of malic acid?

    Malic acid occurs naturally in certain fruits and vegetables. It is also used in some juices, soft drinks, jams, wines and candies to add a sour flavor.

    Good sources of malic acid include apples, cherries, strawberries, papayas, pineapples, oranges, grapes, apricots, mangoes, plums, tomatoes, carrots, olives, peas, potatoes and corn.

  • What is the difference between malic acid and citric acid?

    Malic acid and citric acid are both alpha hydroxy acids that are used in foods for a variety of reasons. Both are also acidic, but malic acid is said to be more acidic than citric acid. Malic acid is also known to increase acidity in foods and other products.

  • Is malic acid harmful to skin?

    Malic acid is generally considered safe to treat certain skin conditions.

    Like other alpha hydroxy acids (AHAs), malic acid may help remove dead skin cells and improve fine lines and other signs of aging. However, it may cause some side effects on the skin, such as rash, itching, irritation, and chemical burns.

Review

All comments are moderated before being published

HealthyPIG Magazine

View all
小朋友叫唔應?可能唔係無禮貌,而係科學:專注時真係聽唔到你

小朋友叫唔應?可能唔係無禮貌,而係科學:專注時真係聽唔到你

小朋友一睇YouTube、打機、畫畫,突然叫佢,佢完全聽唔到。係咪扮聾?係咪發展遲緩?抑或專注力問題? 研究顯示,大部分情況完全正常,與腦部的「選擇性注意力(Selective Attention)」同「過度專注(Hyperfocus)」有關,不代表有疾病。 什麼是「選擇性注意力」?(Sele...
高血壓|隱形殺手的成因、統計數據與科學研究

高血壓|隱形殺手的成因、統計數據與科學研究

  高血壓|隱形殺手的成因、統計數據與科學研究 快速導讀 高血壓係全球最普遍、但最容易被忽視嘅慢性病之一。 超過一半患者完全無症狀,但長期會破壞血管、增加中風同心臟病風險。 主要成因包括:高鹽、肥胖、缺乏運動、低鉀、飲酒、睡眠窒息症、壓力、吸煙、腎病等。 全球研究顯示:高鹽攝取加上肥胖...
為何肺癌早期大多沒有症狀?科學原理、風險因素與早期發現方法全解析

為何肺癌早期大多沒有症狀?科學原理、風險因素與早期發現方法全解析

肺癌一直是全球最常見、死亡率最高的癌症之一。令人憂心的是,大部分肺癌患者在早期(第一、二期)都沒有明顯症狀,往往直到腫瘤擴散、壓迫周邊結構或影響呼吸功能後才被發現。本文以科學角度深入講解:為何肺癌早期「靜悄悄」、身體不察覺?身體內部究竟發生了甚麼? 亦會加入實際的自我檢查策略與醫學建議。 一...
黑眼圈成因全解析:從生理、生活習慣到醫學對策

黑眼圈成因全解析:從生理、生活習慣到醫學對策

前言:為何黑眼圈總是揮之不去? 「黑眼圈」係現代人嘅常見問題之一。無論係通宵工作、壓力過大、過敏,甚至遺傳因素,都可能令眼底皮膚變黑或出現陰影。雖然多數情況屬於美容問題,但有時亦可能反映身體狀況,例如貧血、睡眠質素差、血液循環不良等 [1]。  一、黑眼圈的主要類型與成因 色素型黑眼圈(Pi...
智慧手錶 vs 專用 O₂Ring 血氧儀:血氧監測能力的科學比較

智慧手錶 vs 專用 O₂Ring 血氧儀:血氧監測能力的科學比較

1. 前言 血氧飽和度(SpO₂)是評估呼吸、循環系統狀態的重要指標。近年來,市面上兩大類可穿戴設備用於血氧監測: 智慧手錶(如 Samsung Watch、Apple Watch) 專用血氧監測設備(如 O₂Ring、指夾式脈搏血氧儀) 兩種設備的設計目的、測量方式、準確性、監測...
血氧飽和度、氧氣下降與「警戒線」的科學探討

血氧飽和度、氧氣下降與「警戒線」的科學探討

1. 前言 血氧飽和度(SpO₂)即血液中氧合血紅蛋白佔總血紅蛋白的百分比,是臨床及居家監測呼吸、循環功能的重要指標。當血氧飽和度下降,可能反映體內氧的供應或運送出現問題(低氧血症、hypoxemia)或更廣泛的組織缺氧(hypoxia)[1][2]。本文旨在探討: 血氧飽和度正常範圍與變...
冰敷(Cold Therapy)真正作用全面解析:止痛、減腫,還是幫助修復?|科學視角 + 實證文獻

冰敷(Cold Therapy)真正作用全面解析:止痛、減腫,還是幫助修復?|科學視角 + 實證文獻

冰敷(Ice Pack / Cold Therapy / Cryotherapy)係好多運動、急性受傷(如扭傷、撞擊、肌肉拉傷)時的第一時間處理方法。但不少人會疑惑: 「冰敷純粹止痛,定係真係會幫助組織修復?」「冰敷幾耐?冰敷幾多日?會唔會影響身體自然修復?」 本文從科學、醫學、運動治療角度,...
長時間保持同一姿勢後關節痛、僵硬、郁唔到:成因、科學解釋與改善方法

長時間保持同一姿勢後關節痛、僵硬、郁唔到:成因、科學解釋與改善方法

前言:為何「坐耐、蹲耐、跪耐」之後會痛? 無論係坐喺電腦前、跪低執嘢、長時間翹腳、側睡又唔郁——好多人體驗過一樣情況: 「一動就痛、一企起身腳軟、膝蓋直唔到、關節卡卡聲,又或者要行幾步先鬆返。」 其實呢種情況係非常普遍,而且通常並非關節已經壞死,而係 和關節生理、滑液循環、血液供應、肌肉張力 ...
魚醒味的科學:成因、風險與處理方法全面解析

魚醒味的科學:成因、風險與處理方法全面解析

「魚醒味」是華人烹飪文化中常見的說法,用以描述魚類在 解凍、切片或加熱後所突然出現的腥味、血水味或脂肪味。此現象並不代表食材變壞,但背後牽涉到蛋白質變化、脂肪氧化與揮發性化合物釋放等多種科學機制。本文將以科學角度剖析魚醒味的成因,並提供實證方法降低這種味道,同時探討其安全性。 🧪 什麼是「魚...