當患有乳糖不耐症的人喝牛奶時,罹患第2型糖尿病的風險會降低

A study into the health and genetic predispositions of milk consumers finds that drinking milk reduces the risk of type 2 diabetes in individuals with a genetic transformation that prevents the formation of the protein that separates lactose in milk. . Experts believe that if lactose is retained in the digestive organs without separation, it will become a food hotspot for gastrointestinal microorganisms, thus changing the balance of gastrointestinal microorganisms, which may seriously affect the occurrence of lifestyle-related diseases.

There are mixed claims about this result, with some papers saying it protects against lifestyle-related diseases, others saying it doesn't matter, and some studies finding it does have a negative impact. Milk has a significant effect in preventing type 2 diabetes, according to a recent report which showed that drinking milk with breakfast can reduce subsequent rises in blood sugar levels and suppress appetite.

Some believe that the differences in study results may be due to differences in individual DNA. Research teams from the United States and China previously investigated the daily milk intake of 12,653 Hispanics and Latinos. Use genome-wide association studies (GWAS) to examine the connections.

Most people produce the chemical lactase (used to separate lactose) by the time they are teenagers, but some lactase enzymes are mass-produced in the LTC (LCT) gene. The gene provides instructions for making lactase. This enzyme helps digest lactose, a A sugar found in milk and several other dairy products. People with the change in the enzyme lactase, which is produced by some cells in the wall of the small intestine, are unable to produce lactase as adults. Lactase non-persistence (LNP). Specifically, it is said that half to 80% of Hispanics, 60% to 80% of blacks, and 95% to 100% of Asians are LNP.

Genetic testing found that people with LNP who drank milk regularly had a 30% lower risk of developing type 2 diabetes. In addition, the study also found that for individuals who did not inherit the gene, regular consumption of milk did not change the risk of developing type 2 diabetes.

When the discovery team then analyzed UK Biobank information from 160,000 people living in the UK, similar results were obtained, supporting the findings of the main examination.

Further research also found that increased milk intake was associated with changes in gastrointestinal greening, specifically an increase in Bifidobacterium and a decrease in Prevotella.

LNP does not imply that lactose consumption is off limits. Although there are individual differences in lactose resistance, past research has shown that even people with LNP experience little risk of side effects, assuming they consume 12 grams of lactose per day (12 grams of lactose is equivalent to a large glass of milk). Feeling stressed.

People with LNP cannot process the lactose in milk because their small intestines cannot produce the protein lactase. Undigested lactose in the small intestine then becomes an energy hotspot for gastrointestinal microbes.

Still, the results of this review do not prove cause and effect, for example, drinking milk may help balance gastrointestinal microbes and prevent type 2 diabetes.

The study aimed to investigate the possible effects of milk intake on the gastric microbiota and its metabolites through well-defined clustering, and possible relationships with well-defined health outcomes. The study did not give clear dietary recommendations, and more exploration is expected to explain the benefits of milk against lifestyle-related infections.

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