什麼是己二酸? 它的使用和安全性

describe

Adipic acid, also known as fat acid, is a dibasic acid. Adipic acid occurs naturally in sugar beets and sugar cane , but is produced commercially by oxidizing cyclohexanol with concentrated nitric acid. The result is an odorless white crystalline powder with a slightly sour taste. About 60% of the 2.5 billion kilograms of adipic acid produced each year is used as a monomer in the production of nylon .

E number

The E value of adipic acid is 355.

chemical formula

(CH 2 ) 4 (COOH) 2

Adipic acid for food

Used to adjust the pH (acidity) of food. Used in some calcium carbonate antacids to give them a sour taste. Adds sour flavor to juices and gelatin.

It can also be used as a starch modifier to enable it to withstand heat and freezing.

Adipic acid is often added as the main acid in bottled beverages to create bubbles in the beverage.

Organic acids are used in many powdered food and beverage mixes to provide sweetness.

As an acidifying agent in baking powder, it avoids the undesirable hygroscopic properties of tartaric acid. Since it does not absorb moisture, it helps extend the shelf life of powder products.

Adipic acid is used as a food ingredient as a flavoring. and gelling aids in jelly.

medicinal purposes

Adipic acid has been incorporated into controlled-release formulation matrix tablets to obtain pH-dependent release of weakly basic and weakly acidic drugs.

It is also incorporated into the polymer coating of the hydrophilic monolithic system to regulate the pH within the gel, thereby enabling zero-order release of hydrophilic drugs.

It has been reported that the disintegration of the enteric polymer shellac at intestinal pH is improved when adipic acid is used as a pore-forming agent without affecting release in acidic media.

Other controlled release formulations include adipic acid in order to achieve a late burst release profile.

Is adipic acid toxic to humans?

This substance is generally considered safe when used as a buffer and neutralizing agent in accordance with good production or husbandry practices.

Like most carboxylic acids, adipic acid is a mild skin irritant. It is mildly toxic, with an oral LD50 of 3600 mg/kg in rats.

Skin: May cause skin irritation. Adipic acid has a drying effect on the skin and may cause dermatitis in humans. Ingestion: Ingestion of large amounts may cause gastrointestinal irritation. Inhalation: May cause respiratory irritation.

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