What is triacetin?
Triacetin, also known as triacetin, is a pharmaceutical excipient used in the manufacture of capsules and tablets and has been used as a humectant, plasticizer, and solvent.
Triacetin is a common food additive, used as a solvent for condiments, and has a moisturizing function. Its E number is E1518, and its Australian approval code is A1518. It is used as an excipient in pharmaceuticals and as a humectant, plasticizer and solvent.
It may also function as a parenteral nutrient. It is also used in the perfume and cosmetics industries.
Safety
Triacetin is listed on the FDA's Generally Recognized as Safe (GRAS) list. According to the FDA, triacetin was found to be non-toxic in long-term feeding trials in rats at levels several orders of magnitude higher than what consumers are exposed to. Furthermore, in a 2002 toxicology report, triacetin and a group of related triglycerides did not pose a hazard to human health based on an expected daily intake of 7.8 mg/day/adult and other available data. One case of skin poisoning (allergic contact eczema) resulting from industrial use in cigarette filter production has been reported.
There is no evidence in the available information on triacetin to suggest or indicate reasonable grounds for suspecting that there will be a hazard to the public when triacetin is used at levels that are currently or might reasonably be expected in the future.
- CAS No. 102-76-1
- EC number 203-051-9
- E number E1518
- Chemical formula C9H14O6
Medications using triacetin
- aspirin
- Cetirizine hydrochloride
- Clopidogrel bisulfate
- Cyclobenzaprine Hydrochloride
- Elixir
- Escitalopram oxalate
- Escitalopram oxalate
- Hydroxyzine hydrochloride
- Metformin hydrochloride
- morphine sulfate extended release
- Ondansetron hydrochloride
- sildenafil citrate
- Tamsulosin hydrochloride
- Viagra
